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DOCUMENT GENERAL INFORMATION

TITLE Controlled clinical trials   ESPB13.pdf (288.3 KB)
Document ID LIB250
Document type Policy document
Issue date 01/05/2001
Original language of the document English
Document produced by European Science Foundation
Scientific domains
Policy domains
  • Health

DOCUMENT TEXT

Short description  The reason that interest in controlled trials is required at a European level is because collaboration
in multicentre trials can increase recruitment to trials and the size of the trials which yield statistically more reliable estimates of the effects of health care interventions, both overall and for relevant subgroups. In addition, estimates of these effects, which have been derived from investigations of the same question in a variety of circumstances internationally, can provide insights relevant to the applicability of research results in practice.
It is against this background and rationale that the ESF will take a variety of steps to promote pan-European collaboration in controlled trials.
This statement constitutes the first step, and refers to two further steps that can be implemented without substantial investment from the limited resources available.

Abstract (focusing on the key recommendations)  We are all aware that controlled clinical trials of both drugs and therapies are essential elements in the development of medical research and its transfer into medical practice.
We are also aware that such trials need to be performed on as wide a base of patients as possible and, also, can be very costly. In addition, there are a number of issues in the application of therapeutic or preventive i ...

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