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TITLE Cyclic acid anhydrides - Health-based recommended occupational exposure limit   201002OSH.pdf (679.7 KB)
Document ID LIB632
Document type Scientific advisory body opinion/advice
Issue date 25/01/2010
Document reference ISBN: 978-90-5549-782-9
Original language of the document English
Full text available in EN (679.7 KB)
Document produced by Health Council of the Netherlands organisation visiting card
Document uploaded by Jeannette van Kan
Health Council of the Netherlands
Scientific domains
Policy domains
  • Health


Short description  The Health Council has evaluated the adverse health effects of cyclic acid anhydrides (CAAs) to recommend health-based occupational exposure levels, which specify levels of exposure to airborne substances, at or below which it may be reasonably expected that there is no risk of developing adverse health effects. The primary adverse health effect due to exposure to airborne CAAs is allergic sensitization. No clear threshold level could be found. Alternatively, reference values were calculated: an additional risk of 0.1% due to occupational exposure corresponds to 0.18 µg/m3 for TMA, and 0.007 µg/m3 for HHPA, as an 8-hour time weighted average concentration. Due to insufficient data, no reference values could be determined for other CAAs.
Abstract (focusing on the key recommendations)  Scope
At request of the Minister of Social Affairs and Employment, the Dutch expert Committee on Occupational Exposure Safety (DECOS), one of the permanent committees of experts of the Health Council, proposes health-based recommended occupational exposure limits for chemical substances in the air in the workplace. These recommendations serve as basis in setting legally binding occupational expos ...

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