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TITLE Foot and mouth disease: vaccination revisited   fmd_improcon_en.pdf (3.43 MB)
Document ID LIB64
Document type EC RTD Programmes projects / results
Issue date 09/02/2005
Document reference FMD_ImproCon
Original language of the document English
Document produced by EC-Research and Innovation DG organisation visiting card
Document requested by EC-Research and Innovation DG organisation visiting card
Scientific domains
Policy domains
  • Agriculture


Short description  FMD infection and inoculation with marker vaccines (or highly purified inactivated vaccines) elicit different antibody profiles. FMD_ImproCon seeks to validate existing tests (detecting infection-specific antibodies) for the unequivocal identification of infected animals (vaccinated or not).
Additional aims are to:
· Develop and validate new tests
· Improve virus detection
· Study the onset of vaccinal protection and the impact of vaccination on virus dissemination and the carrier state
· Improve methods used to select vaccine strains
· Develop new marker vaccines (e.g. vaccines that prevent establishment of the carrier state by stimulating mucosal immunity)
Abstract (focusing on the key recommendations)  Foot and mouth disease (FMD) is a highly contagious and devastating disease affecting livestock. EU strategy for controlling FMD outbreaks has relied heavily on mass culling, not only of diseased animals and known (or likely) contacts, but also of animals vaccinated as an emergency containment measure. Today, proposed changes in Union legislation make room for reduced culling, combined with emerge ...

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